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doi: 10.1104/pp.99.4.1597 5 BrzezowskiP.RichterA

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Adipose tissue-specific Bcat2 knockout mice showed resistance to high-fat diet-induced obesity, achieved through enhanced browning and thermogenesis of inguinal white adipose tissue (111)

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The combined effect creates a metabolic state where appetite is significantly reduced, gastric emptying is slowed (meaning food stays in the stomach longer and meals feel more satisfying), insulin dynamics are optimized for fat mobilization rather than fat storage, and resting energy expenditure is elevated through glucagon-mediated thermogenesis

accessed April 2006., [ International Diabetes Federation: Fact sheet: Impaired glucose tolerance (IGT)