A 2-way ANOVA was used to compare differences between GLP-1(2836) and the scrambled control across multiple doses or different mouse strains
Protein kinases: mechanisms and downstream targets in inflammation-mediated obesity and insulin resistance
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In vitro, GLP-1 enhanced brain-derived neurotrophic factor (BDNF) secretion and ameliorated mitochondrial dysfunction and cell toxicity via cAMP/PKA activation in A-treated astrocytes [50]
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Still in testing, results pending