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In a recent FDA drug safety communication regarding SGLT-2 inhibitor-associated DKA, hypovolemia and acute renal impairment were listed as potential factors that may contribute to the development of a high anion gap metabolic acidosis

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Nausea is one of the most frequently reported side effects when starting GLP-1 receptor agonist medications, affecting between 30% and 40% of patients in clinical trials

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The effects of sitagliptin, a DPP-4 inhibitor, on cognitive functions in elderly diabetic patients with or without Alzheimers disease

Pregnancy and breastfeeding: Berberine can be harmful to infants because it can cause a buildup of bilirubin a waste product typically processed by the liver