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Safety monitoring should account for several important risks: Diabetic retinopathy : Patients with existing retinopathy should be monitored closely, particularly if experiencing rapid improvements in blood glucose levels, as this can temporarily worsen eye complications

Heres the pattern healthcare providers tend to see: It often appears early in treatment Its usually mild to moderate It tends to get better as the body adjusts Why does semaglutide cause diarrhea

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In the pooled group of orforglipron recipients who underwent DEXA body composition measurement, mean fat loss was 13.8%, lean mass loss 4.5% and visceral fat mass loss 19%, compared with changes of 1.7%, 0.3% and 7.4%, respectively, in the placebo group