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Thus, introduction of the QMP substitutions in albumin compensates for the decrease in FcRn binding caused by L585 cleavage, without disrupting the pH-dependency of the interaction

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53 The authors noted that failure was typically a result of failure of the eyelet in the absorbable anchor group and suture rupture in the titanium group

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Although we havent seen that in humans yet, it was a side effect noted in animal studies

The clinical results speak for themselves