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In nucleus, the NICD forms ternary complex with LAG-1/CSL DNA binding protein and LAG-3/SEL-8/Mastermind transcription coactivator to activate the expression of target genes (Fig

Alcohol consumption can potentially negatively impact both parts of your immune system, as it disrupts the inflammation signals your body relies upon to distinguish whether it's healthy

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A boiled egg, a big glass of water, and Greek yogurt with berries and a drizzle of nut butter is one simple example

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Furthermore, recombinant LONP1 cleaves serine-rich repeat sequences in c-MYC, disabling its DNA-binding domain and C-terminal MAX-binding site, thereby exerting anticancer effects [164]