In the LEADER trial, over 9,340 patients with type 2 diabetes and high cardiovascular disease risk underwent randomization to liraglutide or placebo and were followed for a median of 3.8 years resulting in a 13% risk reduction in a combined endpoint of death from cardiovascular cause, nonfatal myocardial infarction, or nonfatal stroke [46]

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But what good is oxygen if you cannot use it
Combining them might make you feel worse
In the first few weeks of treatment, your body adjusts to insulin and glucose level changes, which may explain why some people get headaches on GLP-1
Side effects are the most common reason patients hesitate before starting a GLP-1 and the most common reason they stop early