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As a dual GIP and GLP-1 receptor agonist, Zepbound works by enhancing insulin secretion, reducing glucagon levels, and delaying gastric emptying
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When astrocytes undergo glycolysis, glucose is quickly converted into L-lactate, which is then transported out of the cells through monocarboxylate transporters (MCTs)specifically MCT1 and MCT4 on astrocytes and MCT2 on neurons
Participants with T2DM also showed improved HbA1c levels and favorable lipid profile changes (Kapitza et al., 2023)
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