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Beyond weight loss, GLP-1 agents reduce circulating insulin levels, attenuate insulin-like growth factor signaling, and lower systemic inflammatory markers

Targeted overexpression of Igfbp4 in bone using the human osteocalcin promoter results in postnatal growth retardation, altered bone turnover, and low bone mass

Inositol functions as a secondary messenger in insulin signaling pathways and plays a role in cellular processes including glucose metabolism, lipid synthesis, and hormone regulation

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Both of these conditions can lead to serious health issues, some of which can lead to death

These can include nausea, vomiting, diarrhoea, and abdominal cramps