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The innovations in drug design and formulation that we just covered, including dual and triple agonists or conjugates with other hormonal pathways, are helping driving this expansion by delivering greater weight loss and metabolic benefits while reducing side effects through synergistic mechanisms
Together, these findings substantiate our previously made statements that leptin is not a mere passenger to obesity but, rather, a direct driver for weight gain (14)
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Experimental protocols: drugs , doses , administration routes
Snapshot: Ferroptosis
Chronic methylglyoxal infusion by minipump causes pancreatic beta-cell dysfunction and induces type 2 diabetes in Sprague-Dawley rats
J Endocrinol 167 , 447452 (2000)
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