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Amylin receptor agonism thus emerges as an attractive therapeutic target, with the selective amylin receptor agonist eloralintide achieving -20% weight loss with the 9-mg dose after 48 weeks in a phase 2 trial [15]
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In human, the epithelial claudin family has 26 members with different functions
They consist of an amino-terminal GTPase structural domain, two coiled-coil structural domains, and a double transmembrane structural domain embedded in the mitochondrial outer membrane (Joaquim and Escobar-Henriques, 2020)
Eating smaller, lower-fat meals and staying hydrated help significantly
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