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Patients should receive education on: Meticulous skin hygiene and moisturization Prompt treatment of minor wounds Recognition of early infection signs (erythema, warmth, fever) Immediate medical attention for suspected cellulitis Some patients with recurrent cellulitis (typically 3-4 episodes annually) may benefit from prophylactic antibiotics according to Infectious Diseases Society of America guidelines

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Loss of cartilage matrix during OA progression is a combined result of increased catabolic process in cartilage and reduced anabolic activity of chondrocytes