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The internalization and release of iron and its reduction to the ferrous state within the cell involves intracellular ascorbic acid

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In vitro , BBR activated autophagy in podocytes through the mTOR/P70S6K/4EBP1 signaling pathway, enhancing the expression of LC3II/LC3I and the number of autophagosomes, alleviating podocyte apoptosis, and exerting renal protection (Zhang et al., 2021d)

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