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clarified this dilemma by using CRISPR-Cas9 to introduce the risk variant, a non-risk control, and a PTPN22 knockout into human cord blood-derived nave T cells from the same donor

[DOI] [PubMed] [Google Scholar] 26.Kernan WN, Viscoli CM, Brass LM

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They are supplied and purchased under a research-use-only designation , meaning they are intended for in vitro studies, investigational protocols, or experimental applications in line with UK law