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however, in reducing iron deposition, baicalein is superior to deferrioxamine and its mechanism may be related to the up regulation of hepcidin and its regulators bone morphogenetic protein 6 (BMP-6), SMAD family member 4 (SMAD4), and transferrin receptor 2 (TfR2) at the protein and mRNA levels (Dijiong et al., 2019)

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It must be emphasized that this definition [1], unlike the previous ones [2,3,4], does not take into account whether or not EDC interference have specific adverse outcome

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