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While this use is off-label, the mechanistic rationale is sound and the early data is encouraging

The Look AHEAD trial of intensive lifestyle intervention in type 2 diabetes (Pi-Sunyer et al

Many healthy adults use Sermorelin off-label for its potential anti-aging effects (muscle preservation, vitality), though definitive research on anti-aging outcomes is limited

The conversation covers medical therapy, biologic treatments like Tepezza (teprotumumab), surgical options, and the importance of a multidisciplinary approach

10.1016/j.ejphar.2013.11.030 [DOI] [PubMed] [Google Scholar] 130.Liu L, Omar B, Marchetti P, Ahren B

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