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The American Academy of Allergy, Asthma & Immunology distinguishes a normal local reaction (redness or itching only at the injection point) from a hypersensitivity reaction

The inositide lipid PI4P is specifically enriched at the TGN (Weixel et al., 2005), where its generation drives cholesterol and ceramide transport from ER to Golgi through lipid transfer proteins oxysterol-binding protein (Mesmin et al., 2013) and ceramide transport protein (Hanada et al., 2003), respectively

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