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Background of the Pentose Phosphate Pathway (PPP) The pentose phosphate pathway (PPP) was first discovered and characterized in the 1930s by two prominent biochemists, Sir Hans Adolf Krebs and Fritz Albert Lipmann

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To address health-related residual symptoms in the majority of SCD patients in the USA and around the world, it is crucial to maximize non-curative therapies, such as those that do not include stem cell or gene therapy but avoid or abort SCD effects

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