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ROS directly stimulates RIPK1 autophosphorylation, thereby enabling RIPK3 recruitment and necrosome formation (Zhang Y

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These drugs have revolutionized the treatment of obesity, and research also shows that when we use them in people with diabetes, we see a reduced risk of heart attack, stroke, and kidney disease, says Brian Callaghan, MD, FAAN, professor of neurology at the University of Michigan in Ann Arbor