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Bile acid signaling in the regulation of whole body metabolic and immunological homeostasis

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Appropriate amounts can vary per person based on many other factors

Commonly reported side effects include nausea, vomiting, diarrhea, constipation, and abdominal pain

Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) and sodium-glucose cotransporter-2 (SGLT2) inhibitors are game-changers in the treatment of T2DM and are currently promoted by major clinical guidelines among potential first-line pharmacological options after failure/intolerance to metformin, especially in individuals with an atherosclerotic cardiovascular disease phenotype (GLP-1 RAs) [174]