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It binds to GHRH receptors in the anterior pituitary to initiate the production and release of growth hormone

doi: 10.1371/journal.pmed.1001356

A gated start-up strategy can enable controlled acceleration

The trial was recently completed in these patients but only modest changes in hyperphagia without changes in weight were obtained (unpublished data)

Another class of gastric acid inhibitors known as histamine 2 (H 2 )-receptor antagonists (e.g., cimetidine, famotidine, and ranitidine), often used to treat peptic ulcer disease, has also been found to decrease the absorption of vitamin B 12 from food

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