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The therapeutic application of GLP-1 agonists for obesity is grounded in well-established physiological mechanisms that extend beyond glucose regulation to encompass appetite control and energy homeostasis

A spoonful of bitter helps the sugar response go down

Special considerations for specific populations Not everyone approaches GLP-1 drops from the same starting point

2017;7(8) doi: 10.1136/bmjopen-2017-016242

Conclusions These findings suggest that microglial GLP-1R activation in the TNC may suppress the central sensitization of CM by regulating TNC microglial activation via the PI3K/Akt pathway

PubMed pubmed.ncbi.nlm.nih.gov [45] A cost comparison of GLP-1 receptor agonists and bariatric surgery: what is the break even point