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While glutathione skin-lightening creams and injections are available, these uses are more common in Asia, and there are safety concerns with high-dose glutathione for cosmetic purposes

Nutritional assessment and supplementation should be considered, particularly if dietary intake has been reduced due to gastrointestinal side effects

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For people with no neurological involvement Initially administer hydroxocobalamin 1 mg intramuscularly three times a week for 2 weeks, then administer hydroxocobalamin 1 mg intramuscularly every 23 months for life