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309,315 Therapies targeting endothelial function are being explored to prevent or mitigate DPN progression (Fig

Oxidative Stress in Type 2 Diabetes Chronic hyperglycemia drives mitochondrial superoxide production, which depletes intracellular glutathione and raises systemic markers of oxidative damage

For example, a 12-week pilot study found no major changes in hirsutism, likely because the treatment duration was too short

Moreover, peptide analogues that are unimolecular co-agonists of both GLP-1R and GCGR are currently in clinical development for the treatment of T2D, obesity and non-alcoholic steatohepatitis (NASH) 2,3,5,6,7

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Because these medications reduce how much and how often you eat, the quality of the food you choose matters more than ever