There was a complete absence of toxic outcomes or adverse side effects in both trials
Nausea and vomiting hit 22.7% and 11.4% in the 25-mg group, respectively, and dipped to 20% and 7.5% in the 50-mg arm
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doi: 10.1056/NEJMoa012782 19 PfisterDGAngK-KBrizelDMBurtnessBACmelakAJColevasADet al