Patients report amplified nausea, vomiting, diarrhea, constipation, fatigue, dizziness, and electrolyte imbalances
Hormonal signals shift
After 48 weeks of primary treatment, participants in the placebo and 10 mg/kg bimagrumab arms were switched to higher dose bimagrumab therapy for an additional 24-week extension period, explained Penelope Montgomery, MD, Medical Director, Optimal Clinical Trials, New Zealand, who reviewed key aspects of the BELIEVE study design
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Common side effects include nausea, vomiting, diarrhea, and constipation, typically mild and transient during dose escalation
Activation of N-methyl-D-aspartate receptor glycine site temporally ameliorates neuropsychiatric symptoms of Parkinson's disease with dementia