Given the costs associated with these treatments and the observed results, it is recommended to stop DPP-4 inhibitors in patients who do not achieve glycemic targets before introducing a GLP-1 RA, in accordance with current ADA guidelines
PXR: pregnane X receptor
Front Pharmacol 12:634344
Food Choices: What to Favor and What to Avoid Grilled chicken breast, turkey Fish and seafood (salmon, cod, shrimp) Eggs and egg whites Greek yogurt and cottage cheese Beans, lentils, and legumes Lean beef (sirloin, 93% ground) Protein shakes (when appetite is suppressed) Leafy greens: spinach, kale, romaine Broccoli, cauliflower, Brussels sprouts Whole grains: brown rice, quinoa, oats Chia seeds (fiber + protein in small portions) Apples, pears, berries Beans and legumes (fiber + protein) Avocado Olive oil Nuts and seeds Fatty fish (salmon, mackerel) Sodas and sweetened drinks Fruit juices and sports drinks Sweetened coffee drinks Candy, pastries, flavored yogurt Packaged snack foods with added sugar Fried foods (worsens nausea significantly) Fast food Fatty processed meats Chips, crackers, refined snack foods White bread, white pasta, white rice Alcohol (amplifies GI side effects) Spicy or highly acidic foods Large, heavy meals High-fat, high-sodium fast food Unsaturated fats from olive oil, avocado, and fatty fish may support GLP-1 secretion and provide important fat-soluble vitamins (A, D, E, K)
Also Referenced As TH9507 GHRH(1-44) Analogue Trans-3-Hexenoyl-GHRH(1-44)NH Egrifta (clinical brand name) Sourced through an established North American supply partner that conducts onsite manufacturer reviews against documented cGMP practices and applicable ISO quality criteria
NICE, NHS, and MHRA guidance agree: good technique and consistent practice make treatment safer and more comfortable
