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The high fat content can relax the lower oesophageal sphincter and slow gastric emptying further, potentially worsening reflux symptoms when lying down to sleep

Common side effects may include: Nausea Constipation Diarrhea Bloating Stomach discomfort Reduced appetite These symptoms are often most noticeable during dosage increases and may improve as the body adjusts

If youre interested in exploring tirzepatide as part of your weight loss strategy, we encourage you to consult our experienced providers

Ferroptosis is a specific iron-dependent programmed cell death morphologically characterized by changes in mitochondria like shrinkage, disappearance of cristae and outer membrane rupture (Stockwell et al., 2017)

Kouides PA, Abboud CN, Fairbanks VF

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