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In addition, local hypoxic, acidic, and low-glucose environments further augment energy metabolism reprogramming in tumor cells, which not only upregulates antiapoptotic proteins, including protein kinase B (Akt) and hexokinase 2 (HK2) but also inhibits the proliferation of T lymphocytes, facilitating tumor cell immune escape [198]

Do omega-6 fatty acids like LA and GLA, found in many seed oils, promote inflammation in the body

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In microbial pathogens, glutathione can function as a signaling molecule to modulate virulence pathways 21,22,23

Wilson LM, Tharmarajah S, Jia Y, Semba RD, Schaumberg DA, Robinson KA

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