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These included: Nausea (the most frequently reported GI symptom) Vomiting Diarrhoea Constipation Decreased appetite was also commonly reported, though this is better understood as a pharmacodynamic effect of the drug rather than a GI adverse event in the conventional sense

These doses must be titrated against side effect tolerability, as excessive HGH produces acromegaly-like changes and substantial system-wide effects

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Tirzepatide differs from semaglutide because it mimics the GLP-1 hormone and the GIP (glucose-dependent insulinotropic polypeptide) hormone

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