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Fine et al

Rotate sites systematically (abdomen, thighs, upper arms) each week to avoid lipohypertrophy [14]

Niacinamide does not cause the dramatic flush of niacin, so titration to mitigate flushing is usually not necessary

They found that the average frequency of migraine attacks, migraine severity, and drug consumption significantly decreased in both patients with episodic and chronic migraine

The first couple of weeks begin at the lower end of that range, around 6 units, before stepping up to 8 units as the body adapts

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