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Mayo Clinic Proceedings, 89 (9), 13071312

By exploring combination therapies, individuals can find a comprehensive approach that suits their lifestyle and goals, increasing the likelihood of achieving long-term weight management success

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Systemic administration (injectable or oral), which is less common than topical use and not part of approved or standard applications, would theoretically carry different safety considerations requiring appropriate clinical evaluation, though limited research on parenteral administration in animals has suggested acceptable safety profiles at moderate doses