The very high demand combined with the very high prices and limited insurance coverage for these weight loss drugs drove the rise of the market for compounded GLP-1s, says Mike DiStefano, PhD, an assistant professor at the Center for Pharmaceutical Outcomes Research at the University of Colorado in Anschutz
Weight loss surgery can reduce or eliminate hypertension, send type 2 diabetes mellitus into remission, and reduce issues with sleep apnea regardless of the amount of weight lost
Adequate protein intake helps reduce the risk of losing muscle mass while taking GLP-1 medications
Regarding the studies carried out in rats, it has been demonstrated that berberine boosts GLP-1 secretion
These drugs have been studied for more than 30 years, with dozens of large clinical trials proving they are both safe and effective
But coverage of weight loss treatments is less widespread, and navigating the complex insurance landscape can be challenging for patients and time consuming for doctors who prescribe the medications
