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It is effective whether taken orally, due to its systemic effects (1, 6)

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Taplin, M

16,326 In conditions of nutrient excess, as seen in T2DM, insulin resistance blunts insulin-mediated nutrient and energy responses, impairing nerve metabolism and bioenergetic failure

Excitotoxicity is the pathological process by which nerve cells are damaged and killed by excessive stimulation by neurotransmitters such as glutamate

not FDA-approved) use that aims to achieve the therapeutic benefits of the medication, including appetite suppression and improved metabolic health, while significantly reducing the risk and severity of common side effects, which can include issues like bloating, diarrhea, nausea, vomiting, and more