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However, strict adherence to such diets is complicated, which facilitated development of the calorie restriction mimetics (CRM)

It was submitted for regulatory approval in 2025, and results from the OASIS 4 clinical trials showed weight loss of around 13.6%, which is comparable to the injectable version

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Allowing multiple withdrawals from one vial , thanks to the preservative that helps prevent bacterial contamination once the vial has been opened making it more cost-effective and practical for repeated use

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