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The compound exists, for practical purposes, as a subject of academic interest in animal studies and as a product available from gray-market vendors and nowhere else in the supply chain

The available evidence should remain bounded to those research contexts and should not be extended into claims of human or veterinary therapeutic use.

The "two-hit theory" proposed that the initial metabolic disruptions, such as insulin resistance (IR), hyperglycemia, and triglyceride formation in hepatocytes, constitute the first hit, resulting in hepatic steatosis

Muscle-specific PPARgamma-deficient mice develop increased adiposity and insulin resistance but respond to thiazolidinediones

Beyotime, Shanghai, China) was used to detect ROS generation in pancreatic tissue sections

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