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GI side effects are some of the most common for semaglutide, with diarrhea occurring for about 30% of semaglutide users, vomiting for 24.5%, and nausea for about 43.9%

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(Doses typically increase every four weeks.) Novo Nordisk is the manufacturer of the semaglutide injections Ozempic and Wegovy, as well as the oral semaglutide drug Rybelsus