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As a direct antioxidant, GSH quenches reactive oxygen species (ROS), reactive nitrogen species (RNS), and lipid peroxyl radicals, and regenerates oxidised vitamin E and vitamin C back to their active reduced forms placing GSH at the hub of the broader cellular antioxidant network

Chapter 12 - future solutions for osteoarthritis using 3D bioprinting of articular cartilage, in Handbook of surgical planning and 3D printing

Le groupement thiol ragit avec les sels de ces mtaux lourds en crant avec eux une liaison soufre-mtal trs forte pour qu'ils soient ensuite excrts sans causer de dommages l'organisme, hormis la perte de glutathion [7] et une lgre acidification

When intestinal microecology is disrupted, LPS enters blood circulation, activates the Toll-like receptor 4 (TLR4) signaling, and upregulates the expression of the NF-B pathway, which in turn promotes the differentiation and activity of osteoclasts, leading to severe bone loss and osteoporosis (62)

Unlike glutathione, B12 cannot be produced by the body, meaning it must be obtained through diet or supplementation

Vaporciyan AA, Correa AM, Rice DC, Roth JA, Smythe WR, Swisher SG , Walsh GL, Jr PJ