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Patients typically choose the most convenient route when efficacy and safety are comparable

(2021) 27:e13033

NETosis NETosis is a distinctive form of programmed cell death exclusive to neutrophils, which captures and kills pathogens by releasing a network of DNA, histones, and antimicrobial proteins (neutrophil extracellular traps, NETs) [245]

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Some benefits like reduced inflammation and improved recovery may appear within days, while complete tissue regeneration and structural healing continue developing over the full 6-12 week protocol and beyond