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Zhao, B

Curcumin is known to suppress the synthesis of various enzymes such as Mitogen-activated protein kinases (MAPK), cyclooxygenase (COX), lipoxygenase (LOX), Nuclear factor kappa B (NF-B), and others (Panaro et al

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Appropriate timing and amplitude of hormone pulses aid in the production of healthy oocytes and mature, motile sperm

Lipoic acid prevented NOX-induced superoxide production in a rat model of cerebral ischemia and limited infarct volume and neurological deficiencies through upregulating the insulin-phosphatidylinositide-3 kinase (PI3K)-protein kinase B (PKB/Akt) signaling pathway (40)

Available data indicate that THC exhibits a dual, dose-dependent profile, with low-dose exposure engaging adaptive or potentially neuroprotective mechanisms, whereas moderate to high doses, especially following parenteral administration, are associated with glial activation, neuroinflammatory signaling, and functional impairment