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[DOI] [PubMed] [Google Scholar] (188).Xu Y

Dose adjustment: Since the thermogenic effect is dose-dependent, patients on 12mg who find it disruptive may discuss with their physician whether 9mg provides adequate weight loss with a more tolerable thermal profile

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9 The HbA1c reduction was sustained as far out as 78 weeks (58% of patients) and 104 weeks (10% of patients)