The SI 75 value obtained was approximately 2.4, indicating that CPP-CAND also exhibited selectivity for senescent cancer cells induced by other anticancer drugs (Figure
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Pregnancy INCREASES toxicity risk : 80% increase in toxic NAPQI production, 43% higher in first trimester, 33% decrease in safe pathway, and glutathione depleted 36-87%
All these assays were performed according to the manufacturers protocol