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Because GLP-1 drugs already cause nausea in 25-40% of users during dose escalation, cannabis may amplify or mask these signals, making it harder to distinguish expected side effects from harmful reactions

It's important to use semaglutide only under the guidance of a healthcare professional, as they can provide personalized advice on the appropriate dosage, administration, and monitoring to ensure the best outcomes and minimize potential side effects

It is important to note that, in patients with long-standing diabetes and insufficient insulin secretory capacity, the glucose-lowering efficacy of GLP-1 RA is likely to be reduced as a result of diminished incretin effects, and concomitant basal insulin treatment may be required [53]

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Vitamin C is possibly unsafe when taken by mouth in excessive amounts

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