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1 In this study, adverse events considered possibly to be caused by hydroxocobalamin were chromaturia (n=5), pink-to-red skin discoloration (n=3), increase in heart rate (n=1), and elevated blood pressure (n=1)

Decisions regarding therapy resumption should involve a careful risk-benefit discussion with a qualified healthcare professional

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If you have already reconstituted with sterile water, use the entire vial within 24-48 hours or accept a higher contamination risk