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Under normoxic conditions, pyruvate and electron-carrying NADH translocate to the mitochondria, where pyruvate decarboxylation generates acetyl-CoA for entry into the tricarboxylic acid (TCA) cycle, culminating in robust ATP synthesis (25)

Lower thalamic GABA levels may trigger migraine attacks in the early years, resulting in chronically higher cortical glutamate levels later in life, perpetuating the migraine cycle throughout adulthood

DEPs were involved in skeletal and muscular disorders, organismal injury and abnormalities, endocrine system disorder, neurological disease, and hereditary disorder

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