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Overweight individuals with T2DM should reduce energy intake while maintaining a balanced diet rich in nutrient-dense foods like fruits, vegetables, whole grains, lean proteins, and healthy fats, limiting added sugars, sodium, and saturated fats [148]

Most K cells express PC1/3, which cleaves proGIP at Arg65, resulting in the biologically active GIP(142) (Ugleholdt et al., 2006) and stored in secretory granules (450 nm) (Fujita et al., 2010)