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Harikumar KG, Wootten D, Pinon DI, et al

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All books, conference papers, theses, editorials, review articles, meta-analyses, in-vitro studies, laboratory studies, and animal studies were excluded

The most common side effects reported in clinical trials were gastrointestinal symptoms such as: Nausea and/or vomiting Diarrhea Burping Stomach pain Constipation Heartburn These side effects often improve over time as the body adjusted to the medication

Because this study used only de-identified data compliant with the requirements of the Health Insurance Portability and Accountability Act, Institutional Review Board review and approval was not needed