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Table of Contents How the Timeline Works (Biology First) Week 1: Little Visible Change Weeks 2-4: Pigmentation Builds (Loading Phase) Months 1-2: Plateau and Maintenance Months 3-6: Long-Term Pattern Factors That Affect Results When to Adjust Related Reading References How the Timeline Works (Biology First) Pigmentation is not a switch

We observed upregulation of the stemness markers CD133 and CD44 in the CRC DTP cells ( Figure 2E )