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Furthermore, a recent resting-state functional magnetic resonance imaging (MRI) analysis of 18 women with obesity or polycystic ovary syndrome (PCOS) randomized to either 16-week semaglutide or placebo showed no significant changes in brain regions associated with depression and suicidality 177

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There was a significant reduction in the risk of MACE of 3 points (RR 0.87

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