Additionally, while there are many benefits of using the 3xTg mouse model of AD 87 , the use of other AD mouse models could provide additional insight, particularly into whether the benefits of CR are mediated via its remediations of tauopathy
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Neither dosing pattern has been validated in controlled human trials
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Each GPx isoform displays unique cellular localization and substrate affinities, positioning them aptly to counter distinct oxidative threats in specific tissues or cellular regions [48]
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